Research Articles
Combatting Enzyme Deactivation in Organic Solvents: Molecular Insights, Stabilization Strategies, and Clinical Implications
This article provides a comprehensive resource for researchers and drug development professionals tackling the challenge of enzyme deactivation in non-aqueous environments.
Harnessing Light and Enzymes: New Frontiers in Asymmetric Synthesis
This article explores the rapidly evolving field of photoenzymatic enantioselective synthesis, a powerful strategy that merges the energy of visible light with the precise stereocontrol of enzymes.
Enzyme Classification and Catalytic Mechanisms: From Foundational Principles to AI-Driven Prediction in Drug Development
This article provides a comprehensive synthesis of enzyme classification and catalytic mechanisms for researchers and drug development professionals.
Advanced Strategies for Improving Heterologous Enzyme Expression: A Comprehensive Guide for Researchers
This article provides a systematic review of contemporary strategies for enhancing heterologous enzyme expression, addressing critical challenges from foundational concepts to advanced optimization.
Extremozymes vs. Conventional Microbial Enzymes: A Comparative Analysis of Stability for Biomedical Applications
This article provides a comprehensive comparative analysis of the structural stability and functional resilience of extremophile-derived enzymes (extremozymes) against their conventional microbial counterparts.
De Novo Enzyme Design: Engineering Novel Biocatalysts from Scratch for Biomedical Applications
This article provides a comprehensive overview of the rapidly advancing field of de novo enzyme design, a discipline that creates novel protein catalysts with functions not found in nature.
Benchmarking Biocatalysts: A Performance Analysis of Artificial Metalloenzymes vs. Natural Enzymes
This article provides a comprehensive analysis of the performance metrics used to evaluate artificial metalloenzymes (ArMs) against their natural counterparts.
Batch vs. Flow Biocatalysis: A Scalability Assessment for Modern Pharmaceutical Manufacturing
This article provides a comprehensive assessment of the scalability of batch versus continuous flow biocatalysis for researchers and drug development professionals.
Enzyme Immobilization Supports: A Comparative Analysis of Efficiency for Advanced Biocatalysis
This article provides a comprehensive comparison of the efficiency of various enzyme immobilization supports, tailored for researchers and professionals in drug development and biomedical sciences.
Bridging the Annotation Gap: A Comprehensive Guide to Validating Computational Enzyme Predictions for Biomedical Research
The exponential growth of genomic data has far outpaced experimental characterization, leaving public databases rife with erroneous enzyme annotations that misdirect research and drug discovery.