Research Articles
Overcoming Low Substrate Specificity in Engineered Enzymes: AI-Driven Strategies for Precision Biocatalysis
This article addresses the critical challenge of low substrate specificity in engineered enzymes, a major bottleneck in biocatalysis for pharmaceutical and industrial applications.
Combatting Enzyme Deactivation in Organic Solvents: Molecular Insights, Stabilization Strategies, and Clinical Implications
This article provides a comprehensive resource for researchers and drug development professionals tackling the challenge of enzyme deactivation in non-aqueous environments.
Harnessing Light and Enzymes: New Frontiers in Asymmetric Synthesis
This article explores the rapidly evolving field of photoenzymatic enantioselective synthesis, a powerful strategy that merges the energy of visible light with the precise stereocontrol of enzymes.
Enzyme Classification and Catalytic Mechanisms: From Foundational Principles to AI-Driven Prediction in Drug Development
This article provides a comprehensive synthesis of enzyme classification and catalytic mechanisms for researchers and drug development professionals.
Advanced Strategies for Improving Heterologous Enzyme Expression: A Comprehensive Guide for Researchers
This article provides a systematic review of contemporary strategies for enhancing heterologous enzyme expression, addressing critical challenges from foundational concepts to advanced optimization.
Extremozymes vs. Conventional Microbial Enzymes: A Comparative Analysis of Stability for Biomedical Applications
This article provides a comprehensive comparative analysis of the structural stability and functional resilience of extremophile-derived enzymes (extremozymes) against their conventional microbial counterparts.
De Novo Enzyme Design: Engineering Novel Biocatalysts from Scratch for Biomedical Applications
This article provides a comprehensive overview of the rapidly advancing field of de novo enzyme design, a discipline that creates novel protein catalysts with functions not found in nature.
Benchmarking Biocatalysts: A Performance Analysis of Artificial Metalloenzymes vs. Natural Enzymes
This article provides a comprehensive analysis of the performance metrics used to evaluate artificial metalloenzymes (ArMs) against their natural counterparts.
Batch vs. Flow Biocatalysis: A Scalability Assessment for Modern Pharmaceutical Manufacturing
This article provides a comprehensive assessment of the scalability of batch versus continuous flow biocatalysis for researchers and drug development professionals.
Enzyme Immobilization Supports: A Comparative Analysis of Efficiency for Advanced Biocatalysis
This article provides a comprehensive comparison of the efficiency of various enzyme immobilization supports, tailored for researchers and professionals in drug development and biomedical sciences.