Research Articles
AlphaFold2 Beyond Structure: Revolutionizing Enzyme Function Annotation for Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on utilizing AlphaFold2 for accurate enzyme function annotation.
Revolutionizing Biologics: How AI-Driven Excipient Selection is Transforming Enzyme Formulation Stability
This article provides a comprehensive overview of the paradigm shift towards artificial intelligence (AI) in the selection of excipients for enzyme-based drug formulations.
AI-Driven Enzyme Design: Revolutionizing Catalysis Through Electrostatic Preorganization
This article provides a comprehensive analysis of AI-driven enzyme design, focusing on the pivotal role of electrostatic preorganization in enhancing catalytic efficiency.
Dynamic Control, Maximized Yield: How AI is Revolutionizing Gentamicin C1a Biosynthesis
This article explores the transformative role of AI and machine learning in dynamically regulating the biosynthesis of the critical antibiotic component, gentamicin C1a.
From Sequence to Function: How AI and Machine Learning Are Revolutionizing Enzyme Prediction in Drug Discovery
This article provides a comprehensive review of the latest AI and machine learning models transforming enzyme function prediction, a critical task in drug discovery and metabolic engineering.
Beyond Prediction: Validating De Novo Enzyme Structures with AlphaFold2
This article provides a comprehensive guide for researchers on the critical validation of AlphaFold2 (AF2)-predicted enzyme structures.
Revolutionizing Biocatalysis: A Comprehensive Guide to 3D-Printed Reactor Design for Drug Discovery and Development
This article provides a detailed exploration of 3D-printed reactor technology for biocatalytic applications, tailored for researchers and drug development professionals.
Revolutionizing Biocatalysis: Advanced 3D Printing Techniques for Next-Generation Immobilized Enzyme Reactors
This article provides a comprehensive overview of 3D printing as a transformative tool for designing and fabricating immobilized enzyme reactors (IMERs).
Biocatalysis Meets Green Chemistry: 12 Principles for Sustainable Synthesis in Pharma R&D
This article provides a comprehensive analysis of the 12 Principles of Green Chemistry as applied to modern biocatalysis.
Overcoming Low Substrate Specificity in Engineered Enzymes: AI-Driven Strategies for Precision Biocatalysis
This article addresses the critical challenge of low substrate specificity in engineered enzymes, a major bottleneck in biocatalysis for pharmaceutical and industrial applications.