Research Articles
The EC Number System: A Complete Guide for Researchers and Drug Developers
This article provides a comprehensive guide to the Enzyme Commission (EC) number system.
Predicting Enzyme Function: A Comprehensive Guide to EC Number Prediction from Protein Sequences
This article provides a thorough exploration of computational methods for predicting Enzyme Commission (EC) numbers directly from amino acid sequences.
Predicting Substrate Specificity with Deep Learning: EZSpec's Novel Framework for Biomedical Research
This article explores EZSpec, a novel deep learning framework designed to predict enzyme substrate specificity with high accuracy.
Protein Thermal Stability by DSC: Complete Guide for Biopharmaceutical Development
This comprehensive article explores Differential Scanning Calorimetry (DSC) as a critical tool for assessing protein thermal stability in biopharmaceutical research.
Optimizing Multi-Enzyme Cascades: A Comprehensive Design of Experiments (DoE) Guide for Biomedical Researchers
This article provides a complete roadmap for applying Design of Experiments (DoE) to optimize complex multi-enzyme cascade reactions, critical for biocatalysis and pharmaceutical synthesis.
DeepECtransformer vs DIAMOND vs DeepEC: Benchmarking Modern Enzyme Function Prediction Tools for Biomedical Research
This article provides a comprehensive comparison of three leading tools for enzyme function prediction—DeepECtransformer, DIAMOND, and DeepEC—targeted at researchers and professionals in bioinformatics and drug development.
DeepECtransformer Tutorial: Accurate Enzyme Function Prediction for Drug Discovery and Metabolic Engineering
This comprehensive tutorial provides researchers and drug development professionals with a complete guide to implementing DeepECtransformer, a state-of-the-art deep learning model for Enzyme Commission (EC) number prediction from protein sequences.
Unleashing Evolution: A Comprehensive Guide to DNA Shuffling for Protein Engineering and Therapeutic Discovery
This article provides a detailed roadmap for researchers and drug development professionals on DNA shuffling, a cornerstone directed evolution technique.
Extreme Survivors: Unlocking Novel DNA Repair and Protein Homeostasis Mechanisms in Extremophiles for Biomedical Innovation
This article provides a comprehensive analysis of the specialized DNA and protein repair systems that enable extremophiles—organisms thriving in extreme environments—to withstand catastrophic cellular damage.
Circular Dichroism Spectroscopy: A Comprehensive Guide to Analyzing Protein Conformation in Biomedical Research
This definitive guide provides researchers and drug development professionals with a thorough exploration of Circular Dichroism (CD) spectroscopy for protein structural analysis.